KPV is a reference tripeptide (Lys-Pro-Val) corresponding to the C-terminal amino acids of α-melanocyte stimulating hormone (α-MSH 11-13). In academic literature, it is described as a bioactive fragment with signaling activity, also referenced in the larger α-MSH peptide.
Investigated biochemical pathways (academic context)
-
NF-κB signaling: in-vitro models of NF-κB transcriptional activity modulation and monitoring of cytokine production (IL-1β, TNF-α, IL-6) in isolated immune cells.
-
Epithelial integrity models: in-vitro models of interaction with epithelial cells under experimental inflammatory conditions.
-
Antimicrobial assays: in-vitro characterization of antimicrobial activity against selected bacterial strains (academic context of peptide chemistry).
-
Dermal in-vitro models: characterization of interaction with keratinocyte and fibroblast cultures.
-
Cellular uptake: academic interest in the intracellular transport of a short tripeptide in cell models.
Laboratory use and storage
Suitable as a reference standard for HPLC, MS, and in-vitro cell assays. In laboratory practice, the lyophilized powder is reconstituted with sterile diluents, such as Bacteriostatic Water - 10 ml. Store the lyophilisate at -20 °C, protected from light.
Product Purpose
This material is sold exclusively as a reference standard for laboratory and in-vitro research, biochemical analysis, and educational purposes. It is not intended for human consumption, therapeutic use, skin application, ingestion, inhalation, or veterinary use. It is not a drug, dietary supplement, cosmetic, or medical device.
Access
Sales are subject to age verification (18+) and declaration of research or collector's purpose upon order completion.
